100% Three-Year DFS announced with TG4050 and Ph 1 Results Published in Nature Communications
“The publication of these data in Nature Communications, together with the sustained three-year disease-free survival observed with TG4050 monotherapy, represents an important milestone for Transgene,” commented Alessandro Riva, MD, Chairman and Chief Executive Officer of Transgene. “Beyond the encouraging clinical outcomes, the sustained neoantigen-specific immune responses observed over time provide important evidence that our individualized therapeutic vaccine approach can generate durable anti-tumor immunity, strengthening our confidence in TG4050 as a potential new treatment option for head and neck cancer patients at high risk of relapse.”
Share:
More News
AstraZeneca announced the successful completion of the previously announced exclusive license agreement with Dizal Pharmaceutical Co., Ltd for Zegfrovy (sunvozertinib), an oral irreversible epidermal growth factor receptor (EGFR) inhibitor for patients with lung cancer. Through this agreement, AstraZeneca has acquired worldwide rights to develop and commercialise Zegfrovy.
“This agreement represents an important step in our strategy to advance our most promising ADC programs efficiently while preserving long-term value,” said Ashutosh Tiwari, PhD, Chief Executive Officer of Styx Biotechnologies. “This collaboration creates a capital-efficient path to first-in-human development by allowing Styx to clinically de-risk selected programs while preserving
“What is most exciting to us is the depth and durability of the responses we are seeing with INBRX-106, particularly in HPV+ disease,” said Mark Lappe, co-founder and Chief Executive Officer of Inhibrx. “These results strengthen our conviction in OX40-mediated T-cell costimulation and give us a strong rationale to expand
“CD20xCD3 T-cell-engaging bispecific antibodies such as glofitamab and mosunetuzumab have already transformed the treatment of B-cell lymphomas. We are excited to build on that progress in collaboration with Roche,” said Josh Bilenker, M.D., co-founder and Chief Executive Officer of Treeline. “We have generated exciting preclinical data suggesting that TLN-121 enhances