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First Patient dosed in Ph 3 RASolve 308 Trial of Zoldonrasib + Pembrolizumab and Chemo in 1L Metastatic RAS G12D Non-Squamous NSCLC

October 28, 2026

First Patients enrolled in Standard of Care Chemo Combination Cohorts of Global Ph 1/2 ASCEND Trial of CR-001

October 28, 2026

Opamtistomig (PD-L1/4-1BB Bispecific Antibody) Advances to Expansion Stage in Phase II First-Line Gastric Cancer Study

October 28, 2026

University of California, Davis activated as a Clinical Trial Site for Ongoing Ph 1 CERTAIN-T Trial of CER-1236 in Hematologic Malignancies

October 27, 2026

Global Ph 2 Study of Ivonescimab in 1L Clear Cell RCC, Including Combination with Cadonilimab, initiated

October 27, 2026

GOBLET Ph 1/2 study Final Cohort 4 results expected in Q4 2026; initial Cohort 5 results expected in H1 2027

October 20, 2026

Opamtistomig Enrolls First Patient in Ph 1b/2 Combination Trial in Metastatic CRC

October 20, 2026

First Patient Dosed in Hong Kong Clinical Trial of PLT012 for Liver Cancer Expansion

October 20, 2026

First Patient Dosed in Ph 1 Study of MGC030 in Patients with Advanced Solid Tumors

October 20, 2026

First patient dosed in Ph 1 trial of ARR-002 for ovarian and endometrial cancer

October 20, 2026

First Patient dosed in Ph 3 RASolute 309 Trial of RASONQUE™ (daraxonrasib) + Zoldonrasib in 1L Metastatic RAS G12D Pancreatic Cancer

October 14, 2026

Development of vispa-cel in R/R B cell NHL and CB-011 in R/R multiple myeloma to be discontinued

October 14, 2026

First Patient Enrolled in Ph 1b/2 Combination Study of Bexobrutideg in CLL

October 14, 2026

First Patient Enrolled in Global Ph 3 Trial of Cadonilimab vs Nivolumab in 1L Gastric Cancer

October 6, 2026

First patient dosed in Ph 1/2 trial of ARV-6723 in advanced solid tumors

October 6, 2026

First patient dosed with LNK001 in Ph 1 study in patients with advanced or metastatic clear cell RCC

October 6, 2026

Second Patient treated in the Fifth Cohort of Ovarian Cancer FSHR-targeted CAR-T Clinical Trial

October 6, 2026

Selective SMARCA2 degrader program including FHD-909 (LY4050784) to be discontinued

October 6, 2026

IDMC Recommends Continued Ph 2 Development of IMNN-001 Following Favorable Safety Review

October 1, 2026

Enrollment underway in Randomized REO 033 RAS-Mutant, MSS CRC Study

October 1, 2026

Pivotal Ph 3 THIO-104 NSCLC Trial expanded into Spain and Portugal

October 1, 2026

Enrollment underway in pivotal Ph 3 THIO-104 trial in 3L NSCLC patients

October 1, 2026

Target enrollment achieved in registrational TEBE-AM trial with KIMMTRAK® (tebentafusp) in previously treated advanced melanoma

September 22, 2026

Ph 2 ALISCA®-Lung2 Trial of Alisertib + Paclitaxel Initiated for Patients with Advanced SCLC

September 22, 2026

Clinical proof of mechanism for AVA6103 achieved in Ph 1 FOCUS-01 trial

September 22, 2026
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Disclaimer: The OTW team takes care to share authentic information. In case of any discrepancies please write to newsletter@onco-this-week.com. Our website is an aggregator for open-source oncology news. The information on our website is provided without any representations or warranties. OTW is part of RLS Consultants, a global consulting and training firm focusing exclusively on the healthcare and life sciences industries. RLS is a leading provider of opportunity assessment services, utilizing its comprehensive expertise in strategic market research, forecasting, and modeling, as well as pricing and market access to facilitate commercial assessments. RLS does not have any influence on any news reported on OTW. The views and opinions expressed in this article are those of the authors and do not necessarily reflect the official policy or position of RLS. The content on our website is intended strictly for news and information purposes only and should not be treated as a substitute for medical advice, diagnosis, or treatment. News shared on OTW should not be utilized in real-world analytic products as they are based only on limited and dated open-source information.