Azenosertib Fast Track Designation granted for Cyclin E1 positive patients by US FDA

“The data in this manuscript provide functional and mechanistic demonstration that preclinical models with high levels of Cyclin E1 activation are particularly sensitive to azenosertib inhibition, along with supporting clinical data from select patients enrolled in azenosertib clinical studies,” said Mark Lackner, Chief Scientific Officer of Zentalis Pharmaceuticals, Inc. “We believe these data support a biomarker-directed strategy to identify patients most likely to benefit from azenosertib.”

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