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Ph 2 Trial of DNA-Damaging Agent PLX038 initiated in patients with Platinum-Resistant Ovarian Cancer

Drs. Hendrickson and Kaufmann stated, “We are excited to be able to bring this novel treatment to patients with relapsed, platinum-resistant ovarian cancer, in hopes of improving the outcome of this disease.” Added ProLynx co-founder and President Daniel V. Santi “Conventional short-acting topoisomerase 1 inhibitors have clinical activity in platinum-resistant ovarian cancer. Accordingly, we are optimistic that the additional benefits of a long-acting SN-38 will result in increased efficacy and safety in patients treated with PLX038”.

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