Robust T cell Responses Reported Across Diverse HLA backgrounds in Ph 2 AMPLIFY-7P Trial of ELI-002
Robert Connelly, Chief Executive Officer of Elicio, commented, “We are extremely pleased to see that mKRAS-specific T cell responses are induced among patients with a diverse HLA background, suggesting that ELI-002 7P may be applicable to a broad range of PDAC patients potentially addressing a key unmet need and expanding the potential market opportunity. Our observations build on past data to show that the majority of patients express mKRAS-presenting HLAs, likely enabling T cell recognition in most patients. These encouraging findings highlight the potential for ELI-002 7P to benefit a broader spectrum of PDAC patients, which may extend the reach of immunotherapy to more individuals and address a critical unmet need.”
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