Ph 1/2 Study of Vopimetostat in Combination with ERAS-0015 Initiated in patients with MTAP-deleted pancreatic cancer and MTAP-deleted/RAS mutant NSCLC
“The encouraging clinical activity, durability and tolerability observed to date with vopimetostat in combination with RAS inhibition reinforce our belief that co-targeting PRMT5 and RAS represents a promising new frontier in the treatment of pancreatic cancer and potentially other RAS-driven cancers,” said Malte Peters, M.D., President and CEO of Tango Therapeutics. “We are thrilled to initiate this study in partnership with Erasca, a company leading the advancement of RAS-targeted therapies, to evaluate vopimetostat with ERAS-0015 and further explore the potential of this clinically validated and synergistic combination approach.”
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