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American Society of Clinical Oncology Annual Meeting: Conference Coverage

ASCO 2024

  1. AbbVie presents data from ABBV-400, ABBV-706, and Telisotuzumab vedotin trials
  2. Affimed Announces Positive Early Efficacy and PFS Results of AFM24-102 Study in EGFR WT NSCLC
  3. Affini-T Therapeutics to present poster on Ph 1 clinical trial evaluating AFNT-211 targeting KRAS G12V
  4. AffyImmune Announces Presentation on Affinity-Tuned CAR T Therapy AIC100
  5. Agendia Presents New Data on 3-Year Outcome of Chemotherapy Treatment in Patients with Early-Stage Breast Cancer
  6. Agendia Announces New Data Assessing the Immune Active State in HR+/HER2- Early-Stage Breast Cancer
  7. ALX Oncology Presents First Evorpacept Combination Data with an ADC from Ph 1 ASPEN-07 Trial in Patients with Advanced Bladder Cancer
  8. Amgen Presents Innovative Research From Its Oncology Portfolio
  9. Ankyra Therapeutics provides status update on ANK-101 Ph 1 ANCHOR trial
  10. Arvinas presents data of ARV-766 in prostate cancer and TACTIVE-K, a Phase 1b/2 trial with vepdegestrant + atirmociclib (PF-07220060)
  11. Aummune’s Poster to Highlight Ongoing Ph 1 Trial for AM003
  12. Autolus Therapeutics presents longer-term follow-up and additional data analysis of Pivotal Ph 2 FELIX study of obe-cel for adult r/r B-ALL
  13. Black Diamond Therapeutics Presents Promising BDTX-1535 Data in rGBM Patients
  14. BriaCell Doubles PFS and Reports Clinical Benefit Data 
  15. BRUKINSA Data Underscore Differentiated Clinical Profile for Treatment of CLL and SLL
  16. Cantex Pharmaceuticals Announces Four Abstracts Featuring Azeliragon
  17. Corbus Pharma’s SYS6002 (CRB-701) Continues to Demonstrate Encouraging Safety and Efficacy Observed in Patients with Nectin-4 Positive Tumors
  18. Dizal presented the latest data from WU-KONG1 Part B (WU-KONG1B) of sunvozertinib in R/R NSCLC with EGFR exon 20 insertion mutations (exon20ins)
  19. Eikon Therapeutics presents EIK1001 and EIK1001 data
  20. Elicio Therapeutics Announces Preliminary Data from the Ongoing AMPLIFY-7P Ph 1a Study of ELI-002 7P in Patients with mKRAS-driven Solid Tumors
  21. Enhertu demonstrated a mPFS of 13.2 months in HR+ve, HER2-low/ultralow metastatic breast cancer following one or more lines of endocrine therapy
  22. EpicentRx Announces Oral Presentation for TGF-β Ligand Trap, AdAPT-001
  23. First results from late-breaking Ph 3 PALOMA-3 study show five-fold reduction in infusion-related reactions with five-minute SC amivantamab administration
  24. GenFleet Therapeutics Announces Efficacy & Safety Result from Ph 2 Trial for 1L NSCLC Treatment in KROCUS Study, fulzerasib in Combination with cetuximab
  25. Gilead And Arcus Announce Domvanalimab + Zimberelimab And Chemo Exceeded One Year Of mPFS As 1L Treatment For Upper GI Cancers
  26. Gilead And Arcus Announce Etrumadenant + Zimberelimab combo Significantly Reduced The Risk Of Death In 3L mCRC
  27. Grey Wolf Therapeutics Presents First Clinical Data for GRWD5769
  28. GSK presents 25 abstracts including Blenrep and Jemperli results
  29. HUTCHMED announced new and updated data from Ph II study of fruquintinib and surufatinib trials
  30. Imfinzi showed survival benefit in limited-stage SCLC in global Ph III trial, reducing the risk of death by 27% vs. placebo
  31. ImPact Biotech Presents Preliminary Ph 3 Results from ENLIGHTED Study of Padeliporfin VTP in Low Grade Upper Tract Urothelial Cancer
  32. Indaptus Therapeutics Presents New Cohort Data Confirming Original “Pulse-Prime” Hypothesis Via Ph 1 Trial of Decoy20 
  33. Innate Pharma highlights five abstracts selected for publication
  34. Innovent Announces Taletrectinib Updated Data from Ph 2 TRUST-I Study
  35. Innovent Presents Ph 1 Data of IBI363 in Melanoma, Colorectal Cancer and other Solid Tumors
  36. Innovent Presents Data of anti-CLDN18.2 ADC (IBI343) in Patients with Advanced Pancreatic Cancer or Biliary Tract Cancer
  37. Investigational Acasunlimab (DuoBody® -PD-L1x4-1BB) + Keytruda Demonstrate Meaningful Clinical Activity in Ph 2 Trial in Patients with Previously Treated mNSCLC
  38. Ivonescimab Decisively Beats Pembrolizumab, Achieves Statistically Significant Superiority in PFS in 1L Treatment of Patients with PD-L1+ve NSCLC in China
  39. Jacobio Pharma Presents SHP2 + KRAS G12C Data
  40. Jazz Pharma Presents OS & Longer Follow-Up Data from HERIZON-BTC-01 Trial of Zanidatamab in Previously Treated HER2+ve BTC
  41. Johnson & Johnson presents more than 75 clinical study and real-world presentations
  42. Karyopharm Presents Updated Exploratory Subgroup Analyses from SIENDO Study in Patients with Advanced or Recurrent TP53 WT Endometrial Cancer
  43. KRAZATI (adagrasib) Demonstrated Statistically Significant PFS Improvement in Patients with Pretreated Locally Advanced/Metastatic KRASG12C-Mutated NSCLC
  44. Latest analysis of Novartis NATALEE study shows Kisqali® reduces risk of cancer recurrence for early breast cancer patients with high-risk node-negative disease
  45. Legend Biotech presents data from CARTITUDE-2 and -4 studies
  46. Mabwell Announces 9MW2821 Data and Latest Progress
  47. Merck to Present New Data Demonstrating Advancements in Novel Oncology Treatment Approaches Across Broad Portfolio and Diverse Pipeline
  48. Merus’ Petosemtamab in Combination with Pembrolizumab Interim Data Demonstrates Robust Response Rate and Favorable Safety Profile in 1L r/m HNSCC
  49. Merus Presents Interim Data on MCLA-145 Monotherapy and in Combination with Pembrolizumab
  50. Nanobiotix Announces Disease Control and Tumor Response in Patients Treated With RT-Activated NBTXR3 Followed By anti-PD-1 For 2L+ R/M HNSCC Naïve or Resistant to Prior anti-PD-1 Therapy
  51. NeoTX Therapeutics presents preliminary results of naptumomab estafenatox (NAP) and docetaxel in phase 2 trial in patients with advanced/metastatic NSCLC
  52. Nimbus Therapeutics Presents New Positive Monotherapy Ph 1/2 Data of HPK1 Inhibitor in Treatment of Advanced Solid Tumors
  53. NKGen Biotech Publishes Ph 1 Interim Analysis Results of SNK02 Allogeneic NK Cell Therapy in Advanced Solid Tumors
  54. Novartis Scemblix Ph III data first to show superior efficacy with a favorable safety and tolerability profile vs. SoC TKIs in adults with newly diagnosed CML
  55. Nuvation Bio Announces Data from Pivotal Ph 2 TRUST-I Study of Taletrectinib
  56. Obsidian Therapeutics Announces Positive Data from OBX-115 in Patients with Advanced Melanoma
  57. Orca Bio Presents Positive Clinical Outcomes with Orca-T in Patients with AML
  58. Pacylex Pharmaceuticals Reports Zelenirstat Ph 1 safety and efficacy data
  59. Pfizer’s ADCETRIS Regimen Produces Clinically Meaningful Improvement in OS in Patients with R/R DLBCL
  60. Pfizer’s LORBRENA CROWN Study Shows Majority of Patients with ALK-Positive Advanced Lung Cancer Living Beyond Five Years Without Disease Progression
  61. Puma Biotechnology Presented Findings from a Ph II Study of Alisertib in Endocrine-Resistant Metastatic Breast Cancer (TBCRC 041)
  62. Purple Biotech Announces Positive Interim Randomized Ph 2 Data Demonstrating CM24 Improved OS and other Efficacy Endpoints in Pancreatic Cancer
  63. Rakuten Medical Announces Recent Interim Data from Ph 1b/2 Trial of ASP-1929 Photoimmunotherapy + anti-PD-1 for 1L Recurrent and/or Metastatic Head and Neck Cancer
  64. Regeneron presents Anti-tumor Activity of Novel Costimulatory Bispecific Antibody REGN7075 (EGFRxCD28) + Libtayo® (cemiplimab) 
  65. RYBREVANT® (amivantamab-vmjw) + lazertinib showed longer PFS vs osimertinib in 1L treatment of patients with high-risk EGFR-mutated NSCLC
  66. Starpharma announces positive final DEP® irinotecan Ph 2 clinical trial results
  67. Takeda and Pfizer Announce 4-Year Results from Positive Ph 3 HD21 Trial of Additional ADCETRIS® (brentuximab vedotin) Combo in 1L Hodgkin Lymphoma
  68. TILT Biotherapeutics Presents Data on TILT-123 in Ovarian Cancer
  69. Ultimovacs ASA presents data from the Ph II trial INITIUM (NCT04382664)
  70. Updated Data from the Ph 1/2 Study of Olomorasib in KRAS G12C-Mutant Advanced Solid Tumors Presented
  71. VBI Vaccines Announces New Tumor Response Data from Ongoing Randomized Controlled Ph 2b Study of VBI-1901 in rGBM Patients
  72. Werewolf Therapeutics Presents Data from Ongoing Ph 1/1b Trial of WTX-124 as Monotherapy and in Combination with Keytruda in Solid Tumors

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