Data from Ongoing Dose Escalation of BA3182 in Patients with Treatment Refractory Metastatic Adenocarcinoma presented
“BA3182, our dual-CAB EpCAM x CD3 bispecific TCE, was developed to drive maximal binding in the acidic tumor microenvironment, effectively eliminating binding in healthy tissues, and thereby avoiding on-target, off-tumor toxicities observed by others in previous attempts with EpCAM targeting antibodies,” said Jay M. Short, Ph.D., Chairman, Chief Executive Officer and co-founder of BioAtla. “We are observing encouraging preliminary tumor reductions and a reassuring safety profile and continue to dose escalate. BA3182 has the potential to serve over one million patients globally and could be a best-in-class bispecific TCE for multiple solid tumor types.”
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