EMA granted orphan drug status to AB8939 for the treatment of AML
Professor Olivier Hermine, President of AB Science’s Scientific Committee, member of the French Academy of Sciences and Head of the Hematology Department at Necker Hospital, commented: “This designation testifies to the potential of AB8939 for the treatment of AML. Indeed, AB8939 has shown activity as a monotherapy on Ara-C-resistant patient lines, including in unfavorable genetic situations (MECOM, TP53 mutations) that have resisted all treatments administered to date, as well as a synergistic effect with the reference treatments Vidaza® and Venclexta®. The ongoing Phase 1 trial will now evaluate the combination of AB8939 with these reference treatments in refractory patients”.
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