Enrollment of Ph 1 TRE-515 Dose Escalation Trial for Patients with Solid Tumors Completed

“This milestone brings us significantly closer to advancing TRE-515 as the first-to-market dCK inhibitor,” said Dr. Ken Schultz, Trethera’s Chief Executive Officer and Chief Medical Officer. “We remain on track to expand our clinical research in 2026, building on our recent FDA Fast Track designation in prostate cancer.”

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“Fast Track designation in lung cancer represents an important milestone for TRE-515 and further validates our strategy of combining dCK inhibition with targeted cancer therapies,” said Dr. Ken Schultz, Trethera Chairman and CEO. “KRAS G12C inhibitors have transformed the NSCLC treatment landscape, but resistance and incomplete responses remain major challenges.

“AvenCell has built a differentiated cell therapy platform that brings together CRISPR-engineered allogeneic CAR-T technology with a unique switchable CAR approach designed to provide greater control over CAR-T activity,” said Todd Davis, CEO of Ligand. “We believe the combination of these technologies, together with the encouraging clinical data generated to

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“The evERA results represent an important step forward for people with ER-positive advanced breast cancer and underscore the potential for giredestrant to help address the challenge of disease progression in this setting,” said Levi Garraway, MD, PhD, Roche’s Chief Medical Officer and Head of Global Product Development. “Together with the