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Conference Coverage: European Society for Medical Oncology Congress

ESMO 2024

  1. 23andMe Therapeutics Announces Phase 2 Results for Two Additional Cancer Cohorts and Correlative Biomarker Data from 23ME-00610 Study
  2. AbbVie Showcases Advancement of Solid Tumor Pipeline with New Data in Tumor Types with High Unmet Needs
  3. Acrivon Therapeutics Reports Positive Endometrial Cancer Data from Ongoing ACR-368 Registrational Intent Phase 2 Study
  4. Akeso Published First-Ever Efficacy Data for PD-1/VEGF Bispecific Antibody Ivonescimab with or without CD47 Antibody plus FOLFOXIRI for mCRC
  5. Akeso Published Ivonescimab plus Ligufalimab as First-Line Treatment for PD-L1-Positive Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
  6. Amgen presents data from multiple early-stage clinical trials
  7. Antennova to Present Latest Data of ATN-037
  8. Ascendis to Present First Results from Platinum-Resistant Ovarian Cancer (PROC) Cohort of the Ph 1/2 IL-Believe Trial
  9. Ascentage Pharma Releases Latest Data Showing Sustained Clinical Efficacy of Olverembatinib in SDH-Deficient GIST
  10. Avacta Reports Updated Ph 1 Clinical Data of AVA6000 Demonstrating Multiple Ongoing, Durable Responses in Solid Tumors
  11. Bayer presents extensive new data from its oncology portfolio
  12. BioAtla presents poster on Ph 2 trial of ozuriftamab vedotin (BA3021) in patients with R/M SCCHN
  13. BioNTech to Present Clinical Data Updates Across mRNA and Immunomodulatory Oncology Portfolio
  14. Black Diamond Therapeutics Presents Real-World Treatment Practices and Patient Outcomes in Newly Diagnosed NSCLC Patients with Non-Classical Mutations
  15. Bristol Myers Squibb Presents Landmark 10-Year Follow-Up Data from CheckMate -067 Which Showed Continued Durable Long-Term Survival Benefit with Opdivo® plus Yervoy® in Advanced Melanoma
  16. Bristol Myers Squibb to Present Data from Ph 2 RELATIVITY-104 trial exploring the combination of nivolumab, relatlimab (1:1) and chemotherapy as first-line treatment for stage IV or recurrent NSCLC
  17. C4 Therapeutics Presents Monotherapy Data Demonstrating Proof of Mechanism and Early Evidence of Proof of Concept From Ongoing CFT1946 Ph 1 Trial in BRAF V600 Mutant Solid Tumors
  18. Cullinan Therapeutics Presents Positive Updated Data from Module C of Zipalertinib Pivotal Phase 2b Study
  19. Cytovation to present full safety and efficacy data from the CICILIA Phase I/IIa trial evaluating CY-101 in solid tumors
  20. Elevar Therapeutics Reports Advances in HCC and Other Oncology Clinical Programs for Rivoceranib Plus Camrelizumab
  21. Enhertu showed substantial clinical activity in patients with HER2-positive metastatic breast cancer and brain metastases
  22. ESSA Pharma Presents Updated Ph 1/2 Masofaniten (EPI-7386) Clinical Data
  23. Evaxion reports 69% ORR in Ph 2 trial of EVX-01
  24. Exelixis Announces Final Results from Ph 3 Pivotal CABINET Study Evaluating Cabozantinib in Advanced Neuroendocrine Tumors
  25. Harbour BioMed Announces the Latest Clinical Data on the First-in-Class Fully Human Anti-B7H7/HHLA2 Monoclonal Antibody HBM1020
  26. HotSpot Therapeutics Presents First-in-Human Ph 1 Clinical Data on CBL-B Inhibitor, HST-1011
  27. Imfinzi perioperative regimen reduced the risk of recurrence by 32% and the risk of death by 25% vs. neoadjuvant chemo alone in muscle-invasive bladder cancer in the NIAGARA Ph 3 trial
  28. Imfinzi plus Imjudo demonstrated unprecedented overall survival in advanced liver cancer with one in five patients surviving five years in HIMALAYA Phase III trial
  29. Immatics Presents Clinical Proof-of-Concept Data from Ongoing Ph 1 Dose Escalation Trial with TCR Bispecific Molecule TCER® IMA401 Targeting MAGEA4/8 
  30. Immunocore presents Ph 1 data of brenetafusp, an ImmTAC bispecific targeting PRAME, in patients with ovarian cancer
  31. ImmVira Unveils Clinical Results of Intravesical MVR-T3011 for High-Risk BCG-Failure NMIBC Patients
  32. Incyte’s CDK2 Inhibitor INCB123667 Shows Promising Evidence of Clinical Activity in Patients with Advanced Solid Tumors, Notably Ovarian Cancer
  33. Incyte’s Retifanlimab (Zynyz®) Extends PFS in Patients with Squamous Cell Anal Carcinoma (SCAC)
  34. Investigational Rinatabart Sesutecan (Rina-S) Shows Promising Anti-Tumor Activity as Single Agent in Heavily Pretreated Patients with Ovarian and Endometrial Cancers in Ph 1/2 Clinical Trial
  35. IO Biotech Announces Positive Results from Phase 2 Trial of IO102-IO103 in the 1L Treatment of Advanced Head and Neck Cancer
  36. iTeos Announces Clinically Meaningful ORR Observed at Every Dose in Follow-up Interim Analysis of GALAXIES Lung-201 Study of Belrestotug + Dostarlimab in 1L PD-L1 High NSCLC Patients
  37. Jazz Pharmaceuticals Presents Updated Ph 2 Data for Zanidatamab Demonstrating Increased mPFS in HER2-Positive Metastatic Gastroesophageal Adenocarcinoma 
  38. KEYTRUDA + Chemo Before Surgery and Continued as monotherapy After Surgery Reduced Risk of Death by 34% vs neoadjuvant Chemo in High-Risk Early-Stage TNBC
  39. KEYTRUDA + CRT Reduced Risk of Death by 33% vs CRT Alone in Patients With Newly Diagnosed High-Risk Locally Advanced Cervical Cancer
  40. KEYTRUDA + LENVIMA + TACE Significantly Improved PFS vs TACE Alone in Patients With Unresectable, Non-Metastatic HCC
  41. KEYTRUDA + Trastuzumab and Chemo Significantly Improved OS vs Trastuzumab and Chemo Alone in 1L Treatment of Patients With HER2-Positive Advanced Gastric or GEJ Adenocarcinoma
  42. Lantheus Presents Results from the Primary Analysis of Ph 3 Pivotal SPLASH Trial in PSMA-Positive mCRPC
  43. MacroGenics Announces Updated Efficacy & Safety Data from TAMARACK Phase 2 Study of Vobra Duo in mCRPC Patients 
  44. MediLink presents YL201 (B7H3 ADC) with over 6-months PFS in SCLC, and showing pan-tumor benefits
  45. Medivir to present mature clinical data for fostrox + Lenvima
  46. NeoImmuneTech Presents Promising Interim Results of CAR-T Combination with its NT-I7 Asset
  47. New data from TAR-200 Ph 2b SunRISe-1 study show 84% CRR in patients with high-risk NMIBC
  48. Novartis Kisqali® shows deepening benefit in new analysis, reducing the risk of recurrence by 28.5% in a broad population of patients with early breast cancer
  49. NuCana Presents Encouraging Data on NUC-7738 in Combination with Pembrolizumab in PD-1 Inhibitor Refractory and Resistant Melanoma Patients
  50. Nuvalent Highlights Presentation of Clinical Data for Parallel Lead Programs for ROS1 and ALK-positive NSCLC and Accelerated Development Timelines
  51. Nxera’s Partner Cancer Research UK to Present on Ph 1/2a Clinical Trial with Cancer Immunotherapy Drug HTL0039732
  52. PDS Biotech to Present Updated VERSATILE-002 Data
  53. Pfizer’s BRAFTOVI + MEKTOVI Shows Long-Term Clinically Meaningful Response in Patients with BRAF V600E-Mutant mNSCLC
  54. Positive Pooled Data from Nuvation Bio’s TRUST-I and TRUST-II Studies of Taletrectinib in Patients with Advanced ROS1-positive NSCLC announced
  55. Prelude Therapeutics’ SMARCA2 Degrader PRT3789 Demonstrated Promising Initial Clinical Activity and Safety Profile in Ph 1 Trial
  56. Replimune Presents Primary Analysis Data from IGNYTE Clinical Trial of RP1 Combined with Nivolumab in Anti-PD1 Failed Melanoma
  57. RYBREVANT (amivantamab-vmjw) + chemo show 49% ORR in metastatic colorectal cancer
  58. RYBREVANT (amivantamab-vmjw) + chemo shows positive OS trend versus chemotherapy in patients with previously treated EGFR-mutated lung cancer
  59. Scorpion Therapeutics Presents Initial Clinical Data from Ph 1/2 Trial of STX-478 Demonstrating Mutant-Selective PI3Kα Inhibition for the Treatment of Advanced Solid Tumors
  60. Sutro Biopharma Announces Updated Data from Ph 1b Study of Luvelta in Combination with Bevacizumab
  61. Ten-Year Data for KEYTRUDA Demonstrates Sustained OS Benefit vs Ipilimumab in Advanced Melanoma
  62. TILT Biotherapeutics Presents Clinical Data on TILT-123 After Fully Intravenous Delivery Regimen
  63. TORL BioTherapeutics Announces Initial Results of Novel Claudin 6 (CLDN6) Targeted Antibody Drug Conjugate (ADC) TORL-1-23
  64. Transgene and BioInvent’s Oncolytic Virus BT-001 Shows Promising Antitumor Activity in Ongoing Ph I/IIa Trial in Solid Tumors that Failed Previous Treatments 
  65. Ultimovacs Announces Updated Data Analysis on UV1 Ph II NIPU Trial in Mesothelioma

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