FAILED TRIAL: Phase 3 KEYNOTE-B21 trial of adjuvant KEYTRUDA + chemo +/- RT did not meet its primary endpoint of DFS for the treatment of patients with newly diagnosed, high-risk endometrial cancer after surgery with curative intent
“While these results were not what we had hoped, we are focused on continuing to build on the established role of KEYTRUDA in advanced endometrial carcinoma through our approved indications, while rapidly progressing clinical research evaluating KEYTRUDA-based combinations and other investigational candidates, including antibody-drug conjugates, in endometrial and other types of gynecologic malignancies,” said Dr. Gursel Aktan, vice president, global clinical development, Merck Research Laboratories. “We would like to thank all the patients, the investigators and our study collaborators for their participation in this trial.”
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