FDA cleared CTA for LILRB4/CD3 targeting TCE bispecific antibody (6MW5311) for the treatment of AML, CMML, and Multiple Myeloma
U.S. Food and Drug Administration (FDA) has cleared its clinical trial application for its innovative LILRB4/CD3 targeting T Cell Engager (TCE) bispecific antibody (R&D code: 6MW5311), for the treatment of hematologic malignancies (acute myeloid leukemia, chronic myelomonocytic leukemia, and multiple myeloma). 6MW5311 is the first LILRB4/CD3 targeting TCE drug candidate globally to receive IND clearance. Previously, its clinical trial application has also been accepted by the National Medical Products Administration (NMPA) of China.
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