FDA Clears IND Application for AI-081 in Advanced Solid Tumors
“AI-081 leverages two proprietary clinical stage high affinity anti-PD1 and anti-VEGF antibodies designed to further expand the application of checkpoint therapy,” said Yang Liu, PhD, Co-Founder, CEO and Chief Scientific Officer (CSO) of OncoC4. “Through optimal cooperative interactions, AI-081 has displayed superior PD-1 blockade in the presence of VEGF which translates into robust, superior anti-tumor activities in multiple preclinical studies. We look forward to initiating clinical development of AI-081 with the dosing of the first patient in our BIPAVE-001 Phase 1/2 trial in early 2025.”
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