FDA Clears IND Application for PLT012 in Solid Tumors
“PLT012 represents a fundamentally new approach to treating solid tumors by addressing the metabolic dysfunction that underlies immune exhaustion,” said Raven Lin, Ph.D., Co-Founder and CEO, Pilatus Biosciences. “Leveraging our deep expertise in metabolic immunology, PLT012 was developed to simultaneously enhance effector T cell function and suppress tumor-promoting immune populations, while maintaining a favorable safety profile. We believe this dual-action metabolic checkpoint mechanism has the potential to deliver meaningful benefits for patients whose tumors do not respond to existing immunotherapies. We look forward to initiating our Phase 1 clinical trial of PLT012 early next year.”
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