FDA grants Clearance to Initiate First-in-Human Trial of MT-125 in Glioblastoma
“Glioblastoma remains one of the most aggressive and treatment-resistant cancers, with limited advances over the past two decades,” said Dr. Courtney Miller, Founder, and Chief Executive Officer of Myosin Therapeutics. “In collaboration with the Mayo Clinic, we have rapidly advanced our MT-125 program in glioblastoma, and we’re driven and encouraged by the FDA’s clearance to proceed with our first-in-human trial. Preclinical studies suggest targeting non-muscle myosin II represents a uniquely holistic approach to tackling this complex and devastating disease.”
Share:
More News
“These data underscore gotistobart’s potential to redefine treatment for patients with hard-to-treat squamous NSCLC whose disease has progressed after initial therapy and who face limited options,” said Prof. Özlem Türeci, M.D., Co-Founder and Chief Medical Officer at BioNTech. “In second- and later lines of treatment, the clinical relevance of novel
“The collaboration with Ratio represents an exciting opportunity to explore the potential of novel radiopharmaceutical approaches designed to address the complexity and heterogeneity of cancer,” said Ben Hickey, President of RayzeBio. “The combination of our respective technologies and complementary development expertise creates a strong foundation for generating a novel differentiated
“We believe these results mark a potentially important step forward in the treatment of EGFR exon 20 insertion mutation-positive non-small cell lung cancer,” said Fabio Benedetti, MD, Global Chief Medical Officer, Taiho Pharmaceutical. “To address the unmet medical needs of patients and their families, we will continue working closely with
“Recent clinical data validated KAT6 as a targetable mechanism in the treatment of HR+/HER2- breast cancer, including those with actionable mutations,” stated Charles Morris, MBChB, MRCP, Chief Medical Officer of Prelude. “Dual KAT6A/B inhibitors, however, demonstrated overlapping toxicities with current backbone therapies that may limit the utility in earlier lines