First Patient Dosed in Ph 1 Trial of HX044
“We are thrilled to see the first patient entered into clinical study, which marks a significant development milestone for this therapeutic candidate in our pipeline. This achievement demonstrated our strong R&D and clinical development capacity, and it reflects our commitment to addressing unmet medical needs for the patients. We will be working diligently to move this project forward”, said Dr. Faming Zhang, Chairman of Hanx Biopharmaceuticals. “HX044 is a next generation CTLA-4 bispecific antibody fully developed in-house by the company, starting from molecule design. It enhances Treg-depletion function within tumor microenvironment through its effective cis-binding mechanism. It shows strong efficacy even against PD-1-resistant “cold” tumors in preclinical models, demonstrating superior therapeutic potential”, commended by Dr. Henry Li, CEO/CSO of Hanx Biopharmaceuticals.
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