First Patient Dosed in Landmark MYCHELANGELO™ I Trial of OTX-2002 in HCC and Other Solid Tumor Types Associated with the MYC Oncogene
“Today’s announcement marks a new era of therapeutic development utilizing precision genomic control intended to treat and cure serious diseases. As the first-ever Omega Epigenomic Controller™ (OEC) to be dosed in a patient, this milestone for OTX-2002 and the MYCHELANGELO clinical program represents a significant step forward on our mission to deliver a new approach to bringing engineered, programmable mRNA therapeutics to patients,” said Mahesh Karande, President and Chief Executive Officer of Omega Therapeutics. “OTX-2002 leverages our proprietary Omega Epigenomic Programming™ platform and is designed for precise and durable tuning of MYC expression. We look forward to evaluating OTX-2002 for the treatment of HCC, and believe it has the potential to meaningfully transform the treatment landscape for patients in need.”
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