First Patient Dosed in Ph 1/2 Study for KSQ-004EX in advanced solid tumors
“The promise of TIL therapy remains high, but current approaches fall short of addressing the needs of most patients with solid tumors. Preclinically, the combined inactivation of SOCS1 and Regnase-1 in KSQ-004EX strongly increased anti-tumor functionality. We believe these enhancements give KSQ-004EX the potential to significantly advance TIL therapy for the treatment of solid tumors,” said Qasim Rizvi, Chief Executive Officer of KSQ and CEO-Partner at Flagship Pioneering.
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