First Patient Dosed in Ph 1/2 Trial of EB103 in Advanced B-cell NHL
“Dosing our first patient in the STARLIGHT-1 Phase I/II clinical trial is a significant milestone for EB103, ” said Cheng Liu, Ph.D., President and CEO of Estrella Immunopharma. “We believe ARTEMIS T cell therapy could offer unique advantages over current CAR-T therapies, including higher killing efficacy, improved T cell persistence and a better safety profile. We look forward to unlocking its full potential in clinical settings.”
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Dr. Michael Ge, CEO of Kelun-Biotech said, “We are delighted to see the acceptance of the fifth indication application for sac-TMT. Compared to immunotherapy alone, the ADC combination with KEYTRUDA® as first-line treatment for PD-L1-positive NSCLC has achieved not only positive results in PFS, but also a trend toward benefit
“We are excited to work with Merck to advance this promising investigational combination in RAS-driven cancers,” said Jonathan E. Lim, M.D., Erasca’s chairman, CEO, and co-founder. “RAS mutations activate the RAS/MAPK pathway and promote an immunosuppressive environment. Non-clinical data suggest that targeting the pathway with ERAS-0015 may complement PD-1 blockade
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