First Patient Dosed in Ph 1 Trial of KST-6051 in Patients with KRAS-driven Malignancies
“This strategic agreement represents a major validation of our lead pan-KRAS program,” said Dr. Frank Haluska, Chief Executive Officer of Kestrel Therapeutics. “AbbVie’s commitment underscores the potential of our approach to address one of the most important targets in oncology. And dosing the first patient in our Phase 1 trial marks an important step forward in the clinical development of KST-6051. We believe KST-6051 has the potential to address significant unmet medical needs in patients with KRASdriven cancers and look forward to advancing this study and generating initial clinical data with AbbVie.”
Share:
More News
“Fast Track designation in lung cancer represents an important milestone for TRE-515 and further validates our strategy of combining dCK inhibition with targeted cancer therapies,” said Dr. Ken Schultz, Trethera Chairman and CEO. “KRAS G12C inhibitors have transformed the NSCLC treatment landscape, but resistance and incomplete responses remain major challenges.
“AvenCell has built a differentiated cell therapy platform that brings together CRISPR-engineered allogeneic CAR-T technology with a unique switchable CAR approach designed to provide greater control over CAR-T activity,” said Todd Davis, CEO of Ligand. “We believe the combination of these technologies, together with the encouraging clinical data generated to
“Advanced gastric cancer is characterized by substantial biological and clinical heterogeneity. Previous studies have shown that the magnitude of benefit from PD-1 inhibitor therapy is closely associated with PD-L1 expression, and that there remains room to further improve outcomes, particularly in patients with low PD-L1 expression. How to broaden the
“The evERA results represent an important step forward for people with ER-positive advanced breast cancer and underscore the potential for giredestrant to help address the challenge of disease progression in this setting,” said Levi Garraway, MD, PhD, Roche’s Chief Medical Officer and Head of Global Product Development. “Together with the