First Patient dosed in Ph 1b Expansion Cohorts with ADRX-0706 Nectin-4 ADC
“We are pleased to advance the clinical development of ADRX-0706 into the Phase 1b dose expansion cohorts,” said Hui Li, Ph.D., Founder and Chief Executive Officer of Adcentrx. “Encouraging findings from our Phase 1a trial demonstrate the best-in-class potential for ADRX-0706, with differentiated safety and pharmacokinetic properties, including a much lower incidence of critically meaningful AEs for patients, such as peripheral neuropathy. Additionally, the preliminary efficacy responses observed across different dose levels and tumor types provide important clinical validation of Adcentrx’s ADC platform, including the i-Conjugation® technology and novel auristatin payload AP052.”
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