First Patient dosed in Phase 1/2 Trial of IMPT-314 for the Treatment of Aggressive B-cell Lymphoma
“We are pleased to have treated the first patient with IMPT-314 and build on the clinical evidence from the ongoing investigator-led study of this dual-targeted CD19/CD20 CAR T-cell therapy. We believe IMPT-314 may improve tolerability and durability of responses in patients with B-cell lymphomas and therefore has best-in-class potential,” said Jonathan Benjamin, M.D., Ph.D., chief medical officer of ImmPACT Bio. “Safety and efficacy data from this Phase 1/2 study will determine the recommended Phase 2 dose for IMPT-314 and inform on potential cohort expansion opportunities. We expect to present Phase 1 safety and initial efficacy data from patients with relapsed or refractory aggressive B-cell lymphoma in the first half of 2024.”
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