First Patient Dosed with CX-801 in Ph 1 Study in Patients with Solid Tumors
“Interferon-alpha-2b is a powerful immune-modulating cytokine that has demonstrated clinical activity in multiple cancer types such as metastatic melanoma, renal cancer and bladder cancer but its clinical benefit has been limited by significant toxicities when administered systemically. CX-801 utilizes CytomX’s industry leading conditional activation platform to maintain potency and expand interferon’s therapeutic index to potentially become a foundational component of immuno-oncology combination regimens,” said Wayne Chu, M.D., chief medical officer of CytomX Therapeutics.
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