Near Completion of Ph 1 Enrollment for NEO212 Brain Cancer Therapy Announced
“For patients battling brain cancer and other CNS diseases, the ability to deliver more drug to the tumor site with far fewer systemic side effects, could fundamentally shift how we treat these conditions,” said Amir Heshmatpour, Executive Chairman of NeOnc Technologies. “Our clinical results to date underscore the therapeutic potential of NeOnc’s delivery platform to redefine brain cancer treatment and open pathways for application across a broader range of CNS disorders.”
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Richard Saynor, CEO of Sandoz, said: “The global burden of cancer continues to grow and the potential to address unmet patient needs has never been greater. This agreement offers us the chance to reach many more millions of patients, while helping to drive the long-term sustainability of healthcare systems.”
“Beyond the second-line monotherapy opportunity, we and our partners at Pfizer have removed plans for a Phase 3 first-line combination trial with atirmociclib, as well as the planned Phase 3 second-line combination trial with a CDK4/6 inhibitor, from our joint development plan,” continued Dr. Houston. “This decision was made following
“The interim PFS analysis results demonstrated that, compared to the current standard treatment, KN026 in combination with chemotherapy significantly improved PFS, reduced the risk of disease progression or death, and showed a trend toward OS benefit. Detailed data from this study will be presented at an upcoming international academic conference.”
