Orphan Drug Designation Granted to Adze-1.17-CD40L for the treatment of Malignant Glioma

“This important designation is a milestone in the development of our Adze-1.17 oncolytic immunotherapy platform and highlights the need for potential new treatment options for patients with Malignant Gliomas and other difficult to treat cancers,” said Sidney Hopps, Chief Executive Officer of Adze Biotechnology. “The novel Adze-1.17 oncolytic immunotherapy platform is designed for both systemic and intra-tumoral delivery of immunotherapy payload combinations to various types of solid tumors. We look forward to advancing this therapy into the clinic.”

Share:

More News

PharmaMar has submitted a Marketing Authorization Application to the European Medicines Agency for Zepzelca® (lurbinectedin) in combination with atezolizumab (Tecentriq®) for the maintenance treatment of adult patients with extensive-stage small cell lung cancer, whose disease has not progressed after first-line induction therapy with atezolizumab, carboplatin and etoposide. The MAA submission

“At SR One, our mission is to invest in companies that we believe have the ability to innovate and advance transformational new therapies in areas of high unmet medical need,” said Simeon George, M.D., Chief Executive Officer and Managing Partner at SR One. “Fore Bio is focused on resetting the

The study demonstrated a statistically significant and clinically meaningful improvement in the primary endpoint of TACE-progression-free survival (TACE PFS*), and the other primary endpoint of overall survival (OS) is immature at the prespecified first interim analysis. Meanwhile, a clinically meaningful PFS by RECIST v1.1** was also observed. Detailed findings from

“The positive CHMP recommendation for the Itovebi-based regimen represents a significant step towards providing people in the EU with PIK3CA-mutated, ER-positive advanced breast cancer with a targeted therapy in the first-line setting,” said Levi Garraway, M.D., Ph.D., Roche’s Chief Medical Officer and Head of Global Product Development. “This recommendation is