Ph 1b Data for Tegavivint + Osimertinib combo in 1L EGFR-Mutated NSCLC Announced

“These promising results provide important early clinical evidence supporting tegavivint’s differentiated mechanism of action and its potential to address one of the fundamental limitations of targeted cancer therapy: the persistence of drug-tolerant tumor cells,” said Rahul Aras, Ph.D., President and Chief Executive Officer of Iterion Therapeutics. “We are particularly excited by the depth of tumor reduction, complete responses and survival observed in this study, together with the favorable tolerability profile of the combination. We believe these data provide important clinical validation for targeting β-catenin signaling and support the continued development of tegavivint in combination with targeted cancer therapies.”

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