Ph 2 Study of Opaganib and Darolutamide Initiated in metastatic CRPC
“Prostate cancer is the second most diagnosed cancer in the world with around 1.5 million new cases per year, causing the death of almost 400,000 men every year, while millions more men are living with prostate cancer resulting in a significant burden of disease,” said Dr Mark Levitt, RedHill’s Chief Scientific Officer. “Men with mCRPC have few treatment options available to them, and those positive for the PCPro marker of ARPI-resistance seem to have a particularly poor prognosis. Darolutamide is establishing itself as a key therapy in the treatment of prostate cancer, a market worth approximately $12 billion in 2023, and, if the addition of opaganib can reduce the resistance to darolutamide therapy, this could represent a significant breakthrough in improving the ability to manage advanced treatment-resistant mCRPC for improved outcomes.”
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