Pol θ inhibitor SIM0508 obtained IND approval from US FDA
“The investigational new drug (IND) application of SIM0508, a DNA polymerase θ (Pol θ) small molecule inhibitor, has been approved by the Food and Drug Administration (FDA). Currently, the antitumor candidate has been cleared to carry out clinical trials in patients with locally advanced/metastatic solid tumor in both China and the United States.”
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