Positive Ph 2 Translational Data of IMNN-001 in Advanced Ovarian Cancer Presented
“We are encouraged by these translational data being presented at the ESMO Gynaecological Cancers Congress 2025, which strongly complement the compelling overall survival results from the OVATION 2 trial presented at ASCO 2025,” said Douglas V. Faller, M.D., Ph.D., Chief Medical Officer of IMUNON. “The clinical outcomes, showing a robust increase in overall survival for women with advanced ovarian cancer treated with IMNN-001 plus standard-of-care chemotherapy, align with these pharmacological and immunopathological findings. These results validate that IMNN-001 induces IL-12 and its downstream anti-tumor effectors, IFN-γ and TNF-α, exclusively at the tumor site with minimal systemic exposure, supporting our ongoing Phase 3 OVATION 3 trial.”
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