Positive Topline Results from Ph 2/3 Registrational Trial (OptimUM-02) of Darovasertib – Crizotinib combo in 1L HLA-A*02:01-neg Metastatic Uveal Melanoma Announced
“OptimUM-02 is the first randomized study to demonstrate a statistically significant and clinically meaningful benefit in PFS in the clinical setting of first-line HLA-A*02:01-negative metastatic uveal melanoma. For patients with uveal melanoma, these results potentially offer a new treatment option that delivers a significant clinical advancement in both PFS and ORR versus currently available therapies,” said Yujiro S. Hata, President and Chief Executive Officer, IDEAYA Biosciences.
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