TroFuse-005 Trial of Sacituzumab Tirumotecan (Sac-TMT) Met OS/PFS Primary Endpoints in Certain Patients With Advanced or Recurrent Endometrial Cancer

“The scale and ambition of our expansive TroFuse program reflects our deep commitment to advancing one of the industry’s leading ADC pipelines to make a difference for more people facing cancer and builds on our legacy of leadership in gynecologic cancer research,” said Dr. Dean Y. Li, president, Merck Research Laboratories. “These findings reinforce our belief that sac-TMT, with its proprietary bifunctional linker designed with the intent to maximize payload delivery to tumors while minimizing impact on healthy cells in the body, has the potential to become a cornerstone in the treatment of certain patients with advanced endometrial cancer. We thank the patients and investigators for participating in our studies as well as our collaborators at Kelun-Biotech for helping us advance this important treatment.”

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