Two Ph 2 trials of Samuraciclib + SERDs in HR+ve Advanced Breast Cancer demonstrate extended PFS in patients without TP53 mutations or without liver mets

“Based on the results from these two independent studies, we have identified patient populations showing improved progression-free survival, highlighting the potential of samuraciclib in combination with SERDs as an effective new treatment option for these patients. Carrick is further validating these two selection strategies in two additional Phase 2 studies reading out later this year with the intent to advance to Phase 3 in 2026, enriching for one of these two patient groups,” said Tim Pearson, Chief Executive Officer of Carrick Therapeutics.

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