Updated Survival Data Presented from Ph 3 Trial of DCVax®-L For Glioblastoma Using Individual Patient Level Data in Multiple Independent Analyses

“These new PSM and IPW analyses, together with the E Value and Rosenbaum’s Gamma sensitivity analyses, provide strong evidence and reinforcement of the survival benefit with DCVax-L treatment, based on my review of the statisticians’ analyses,” commented Dr. Marnix Bosch. “The key is that all of these analyses, which have taken multiple different approaches and have applied them to multiple ndGBM RCTs, have produced results that are all directionally consistent and all in the same range of magnitude. The statisticians’ findings indicate that the median survival benefit reported from the original analysis of the DCVax-L Phase III trial, based on cohort-level data, was likely substantially underestimated.”