WCLC 2025: New HERNEXEOS® data demonstrated promising intracranial responses in patients with advanced HER2m NSCLC with brain mets 

“This data update showcases zongertinib’s strong efficacy and safety profile in patients with HER2-mutant non-small cell lung cancer with and without brain metastases,” said the presenting investigator, Dr. Gerrina Ruiter, MD., PhD., at the Department of Clinical Pharmacology and Thoracic Oncology, Netherlands Cancer Institute, Netherlands. “Patients with brain metastases historically have had a very poor prognosis and few effective treatment options. These data showed zongertinib is active in the brain and underscore its potential for patients who have not received prior radiotherapy.” 

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